System Configuration : System Setup : Configuring Pro Tools Hardware Settings : Configuring Default Sample Rate Setting in Hardware Setup

Configuring Default Sample Rate Setting in Hardware Setup
The Sample Rate setting in the Hardware Setup dialog determines the default sample rate when you create a new session. This setting is available only when there is no session open. Otherwise, the current session sample rate is displayed, but cannot be changed.
With Avid HDX, Pro Tools|HD, and HD Native hardware, you can change the default Sample Rate in the Hardware Setup, or in the Playback Engine.
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With Avid HDX, Pro Tools|HD, and HD Native hardware, the Sample Rate setting can affect the number of available voices.
On Pro Tools, you can only change the default sample rate in the Hardware Setup or using the control panel for M-Audio and third-party audio interfaces.
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You can change the sample rate when creating a new Pro Tools session by selecting a different sample rate in the New Session dialog.
To change the default Sample Rate in the Hardware Setup:
1 Choose Setup > Hardware Setup.
2 Select the sample rate from the Sample Rate pop-up menu.
3 Click OK.